Objectives:

To evaluate the long-term changes in anterior segment morphology after laser peripheral iridotomy (LPI) in eyes with primary angle-closure suspect (PACS), primary angle closure (PAC), and primary angle-closure glaucoma (PACG) using Scheimpflug camera (SC).

Materials and Methods:

Fifty-six eyes of 30 patients diagnosed as PACS, PAC, and PACG were included prospectively in this study. In addition to full ophthalmic examination and intraocular pressure (IOP) assessment, anterior-posterior length (AxL) values of the eyes were recorded. With use of SC, average anterior chamber angle (AACA), central anterior chamber depth (CACD), and anterior chamber volume (ACV) were documented preoperatively and at 1 month, 3 months, 6 months, and 12 months after LPI. The results have been evaluated statistically.

Results:

There was no statistically significant difference between the groups in terms of mean age, gender, and AxL (p>0.05). AACA, CACD, and ACV measurements showed significant difference between baseline and months 1.3, 6, and 12 in all groups (p<0.05). AACA was statistically significantly decreased between months 6 and 12 in PACS group; between months 1 and 12, months 3 and 12, months 6 and 12 in PAC and PACG groups (p<0.05). CACD measurements demonstrated statistically significant decrease between months 6 and 12 in PAC group, between months 3 and 6, months 3 and 12 in PACG group (p<0.05). ACV was statistically significantly decreased between months 6 and 12 in PAC group, between months 1 and 12, months 3 and 12 in PACG group (p<0.05).

Conclusion:

LPI led to dramatic changes in anterior segment morphology. In our study, the course of the changes caused by LPI was observed through one-year follow-up with SC. In the early period, a positive effect on all parameters was detected. The trends in the course of measurements should be followed up for longer time in larger series to investigate whether the changes show continuity or not.

Keywords: Laser peripheral iridotomy, primary angle-closure suspect, primary angle closure, primary angle-closure glaucoma, Scheimpflug camera